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Endocannabinoid concentrations in major depression: effects of childhood maltreatment and relation to hippocampal volume

Abstract Evidence from preclinical animal models suggests that the stress-buffering function of the endocannabinoid (eCB) system may help protect against stress-related reductions in hippocampal volume, as is documented in major depressive disorder (MDD). However, stress exposure may also lead to dy...

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Principais autores: Raegan Mazurka, Kate L. Harkness, Stefanie Hassel, Niclas Stensson, Nikita Nogovitsyn, Jordan Poppenk, Jane A. Foster, Scott D. Squires, Jessie Rowe, Roumen V. Milev, Katherine E. Wynne-Edwards, Gustavo Turecki, Stephen C. Strother, Stephen R. Arnott, Raymond W. Lam, Susan Rotzinger, Sidney H. Kennedy, Benicio N. Frey, Leah M. Mayo
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2024-10-01
Series:Translational Psychiatry
Acceso en liña:https://doi.org/10.1038/s41398-024-03151-z
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