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TIGIT signaling and its influence on T cell metabolism and immune cell function in the tumor microenvironment

One of the key challenges for successful cancer therapy is the capacity of tumors to evade immune surveillance. Tumor immune evasion can be accomplished through the induction of T cell exhaustion via the activation of various immune checkpoint molecules. The most prominent examples of immune checkpo...

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Auteurs principaux: Nouria Jantz-Naeem, Romy Böttcher-Loschinski, Katrin Borucki, Marisa Mitchell-Flack, Martin Böttcher, Burkhart Schraven, Dimitrios Mougiakakos, Sascha Kahlfuss
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2023-02-01
Collection:Frontiers in Oncology
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fonc.2023.1060112/full
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