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Implications of the Nucleocapsid and the Microenvironment in Retroviral Reverse Transcription

This mini-review summarizes the process of reverse-transcription, an obligatory step in retrovirus replication during which the retroviral RNA/DNA-dependent DNA polymerase (RT) copies the single-stranded genomic RNA to generate the double-stranded viral DNA while degrading the genomic RNA via its as...

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Principais autores: Marylène Mougel, Andrea Cimarelli, Jean-Luc Darlix
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2010-04-01
Serier:Viruses
Fag:
reverse transcriptase
nucleocapsid protein
genomic RNA
viral DNA
strand transfers
SEVI
Online adgang:http://www.mdpi.com/1999-4915/2/4/939/
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