Sex hormones and serotonin 4 receptor brain binding in men with and without major depressive disorder

Sex hormones may contribute to the pathophysiology of Major Depressive Disorder (MDD) through effects on the serotonergic brain system. Estradiol is associated with serotonergic neurobiology in rodent models and humans across sexes. In healthy men, we have previously observed a negative association...

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Hlavní autoři: Malene Ravn Aarestrup, Kristian H. Reveles Jensen, Søren Vinther Larsen, Brice Ozenne, Kristin Köhler-Forsberg, Gitte Moos Knudsen, Martin Balslev Jørgensen, Vibe G. Frokjaer
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2025-01-01
Edice:Neuroscience Applied
Témata:
5-HT4 receptor
Positron emission tomography (PET)
Major depressive Disorder (MDD)
Estrogen
Testosterone
Sex Hormones
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2772408525001097
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