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ASM is a therapeutic target in dermatomyositis by regulating the differentiation of naive CD4 + T cells into Th17 and Treg subsets

Abstract Background This study aims to investigate the involvement of acid sphingomyelinase (ASM) in the pathology of dermatomyositis (DM), making it a potential therapeutic target for DM. Methods Patients with DM and healthy controls (HCs) were included to assess the serum level and activity of ASM...

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Autores principales: Yuehong Chen, Huan Liu, Zhongling Luo, Jiaqian Zhang, Min Dong, Geng Yin, Qibing Xie
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2024-07-01
Colección:Skeletal Muscle
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Acceso en línea:https://doi.org/10.1186/s13395-024-00347-1
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