Formulations, Hemolytic and Pharmacokinetic Studies on Saikosaponin a and Saikosaponin d Compound Liposomes

The aim of this study was to develop and optimise a saikosaponin a and saikosaponin d compound liposome (SSa-SSd-Lip) formulation with reduced hemolysis and enhanced bioavailability. A screening experiment was done with Plackett–Burman design, and response surface methodology of five factors (EPC/SS...

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主要な著者:	Guo-Song Zhang, Peng-Yi Hu, Dong-Xun Li, Ming-Zhen He, Xiao-Yong Rao, Xiao-Jian Luo, Yue-Sheng Wang, Yu-Rong Wang
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2015-04-01
シリーズ:	Molecules
主題:	saikosaponin a saikosaponin d liposomes formulations hemolytic pharmacokinetic
オンライン･アクセス:	http://www.mdpi.com/1420-3049/20/4/5889
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