MCAM interacts with integrin β1 to promote EGFR-TKI resistance in lung adenocarcinoma through the JAK3 signalling pathway

Abstract Background Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have exhibited remarkable efficacy against EGFR-mutated lung cancer. However, the majority of patients receiving EGFR-TKIs face a grim prognosis due to acquired drug resistance. Melanoma cell adhesion molec...

全面介紹

書目詳細資料

Principais autores:	Saiqun Zhang, Yuling Chen, Chang Li, Jian Zhao, Min Jiao, Mengzhu Zhang, Chenkang Ma, Anqi Wang, Jianjun Li, Yuanyuan Zeng, Jianjie Zhu, Chuanyong Mu, Jian-an Huang, Zeyi Liu
格式:	Artigo
語言:	Inglês
出版:	BMC 2025-07-01
叢編:	Journal of Translational Medicine
主題:	EGFR-TKIs MCAM Integrin β1 JAK3 Resistance
在線閱讀:	https://doi.org/10.1186/s12967-025-06874-9
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!