Promotion of colorectal cancer by transcription factor BHLHE40 involves upregulation of ADAM19 and KLF7

BHLHE40 is a transcription factor, whose role in colorectal cancer has remained elusive. We demonstrate that the BHLHE40 gene is upregulated in colorectal tumors. Transcription of BHLHE40 was jointly stimulated by the DNA-binding ETV1 protein and two associated histone demethylases, JMJD1A/KDM3A and...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Yuan Sui, Hanlin Jiang, Collyn M. Kellogg, Sangphil Oh, Ralf Janknecht
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2023-02-01
Цуврал:	Frontiers in Oncology
Нөхцлүүд:	colorectal cancer gene transcription ADAM19 KLF7 BHLHE40 RNA sequencing
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1122238/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!