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Inhibition of basal IL-6 activity promotes subcutaneous fat retention in humans during fasting and postprandial states

Summary: Interleukin-6 (IL-6) knockout mice and humans treated with IL-6 receptor blockade gain adipose tissue mass. This study investigates whether basal IL-6 activity (resting IL-6 levels) influences fat storage during fasting and postprandial states. Using stable-isotope tracer techniques and IL-...

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Principais autores: Beckey Trinh, Signe Johanne Rasmussen, Mathilde Ehnhuus Brøgger-Jensen, Christoph Andreas Engelhard, Anton Lund, Ana Rita Tavanez, Alexandra Vassilieva, Susanne Janum, Ulrik Winning Iepsen, Bente Kiens, Kirsten Møller, Bente Klarlund Pedersen, Gerrit Van Hall, Helga Ellingsgaard
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2025-04-01
סדרה:Cell Reports Medicine
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גישה מקוונת:http://www.sciencedirect.com/science/article/pii/S2666379125001156
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