Normalization of RNA-sequencing data from samples with varying mRNA levels.

Methods for normalization of RNA-sequencing gene expression data commonly assume equal total expression between compared samples. In contrast, scenarios of global gene expression shifts are many and increasing. Here we compare the performance of three normalization methods when polyA(+) RNA content...

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Podrobná bibliografie

Hlavní autoři:	Håvard Aanes, Cecilia Winata, Lars F Moen, Olga Østrup, Sinnakaruppan Mathavan, Philippe Collas, Torbjørn Rognes, Peter Aleström
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2014-01-01
Edice:	PLoS ONE
On-line přístup:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089158&type=printable
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