Decoding the mitochondrial connection: development and validation of biomarkers for classifying and treating systemic lupus erythematosus through bioinformatics and machine learning

Abstract Background Systemic lupus erythematosus (SLE) is a multifaceted autoimmune disease characterized by clinical and pathological diversity. Mitochondrial dysfunction has been identified as a critical pathogenetic factor in SLE. However, the specific molecular aspects and regulatory roles of th...

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Detalhes bibliográficos

Principais autores:	Haoguang Li, Lu Zhou, Wei Zhou, Xiuling Zhang, Jingjing Shang, Xueqin Feng, Le Yu, Jie Fan, Jie Ren, Rongwei Zhang, Xinwang Duan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-12-01
coleção:	BMC Rheumatology
Assuntos:	Systemic Lupus Erythematosus (SLE) Mitochondria-related genes (MRGs) Biomarkers Bioinformatics Machine learning
Acesso em linha:	https://doi.org/10.1186/s41927-023-00369-0
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