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Proton-pump inhibitor exposure and prevalence of colorectal adenoma: a retrospective analysis from the Sakkopi study

Objective Proton-pump inhibitors (PPIs) are among the most widely prescribed long-term medications worldwide, yet concerns remain about their potential role in colorectal carcinogenesis. Experimental data suggest that PPI-induced hypergastrinaemia may promote colonic epithelial proliferation, but ep...

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Auteurs principaux: Bernhard Wernly, Elmar Aigner, Christian Datz, Maria Flamm, Georg Semmler, Hannah Hofer, Sarah Wernly, Andreas Völkerer, Laurenz Hauptmann
Format: Artigo
Langue:Inglês
Publié: BMJ Publishing Group 2026-01-01
Collection:BMJ Open Gastroenterology
Accès en ligne:https://bmjopengastro.bmj.com/content/13/1/e002117.full
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