DposFinder: an interpretable transformer model for predicting phage-derived polysaccharide depolymerases and their host capsular serotypes

Abstract Background Polysaccharide depolymerases derived from phages play a pivotal role in the degradation of bacterial surface polysaccharides, offering a promising strategy to address antibiotic-resistant bacterial strains. However, the identification of these enzymes along with their associated...

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Bibliografske podrobnosti

Principais autores:	Yanxiang Shen, Heyuan Lun, Yumeng Zhang, Zhikang Wang, Cui Tai, Xiaohua Chen, Jiangning Song, Ping He, Hong-Yu Ou
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2026-04-01
Serija:	Genome Medicine
Teme:	Polysaccharide depolymerase Capsular serotype Phage therapy Klebsiella pneumoniae Transformer
Online dostop:	https://doi.org/10.1186/s13073-026-01657-3
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