Enhanced genome replication activity of pandemic H1N1 influenza A virus through PA mutations
ABSTRACT The 2009 pandemic H1N1 (pH1N1) influenza A virus (IAV) is a reassortant virus with two polymerase components, PA and PB2, originating from avian IAV. Avian IAV polymerase does not function efficiently in mammalian cells without host-adaptive mutations. The mechanism by which pH1N1 replicate...
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| Formaat: | Artigo |
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American Society for Microbiology
2026-02-01
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| Reeks: | Journal of Virology |
| Onderwerpen: | |
| Online toegang: | https://journals.asm.org/doi/10.1128/jvi.01391-25 |
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