Neutrophil extracellular traps are associated with poor response to neoadjuvant therapy and poor survival in pediatric osteosarcoma

PurposeOsteosarcoma (OS), the most common primary bone malignancy in childhood poses a therapeutic challenge despite extensive research. Neutrophil extracellular traps (NETs) play a role in the tumor microenvironment (TME) in a variety of cancers, but their role in OS has not been characterized.Expe...

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Detalhes bibliográficos

Principais autores:	Szilvia Baron, Yoav Binenbaum, Ronny Maman, Victoria Fidel, Anna Shusterman, Dmitry Vaisman, Osnat Sher, Michal Manisterski, Rachel Shukrun, Claudia Rössig, Ronit Elhasid
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-03-01
coleção:	Frontiers in Oncology
Assuntos:	osteosarcoma tumor microenvironment (TME) neutrophil neutrophil extracellular traps (NETs) T cell chemotherapy resistance
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1472716/full
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