Investigating the anti-filarial efficacy and molecular interactions of thiadiazol derivative: Insight from quantum chemical calculations, pharmacokinetics, and molecular docking studies

Parasitic infections such as lymphatic filariasis (elephantiasis) solely result from the infestation of a slender and thread-like worm. This condition precipitates swelling, often accompanied by skin alterations, potentially leading to substantial disability and disfigurement. Recent advancements in...

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Principais autores:	Eze A. Adindu, Bassey O. Ekpong, Musa Runde, Aondoungwa M. Atotse, Folasade O. Ojumola, Alpha O. Gulack, Aniekan E. Owen, Solomon O. Iyam, Michael O. Odey, Innocent Benjamin, Terkumbur E. Gber, Hitler Louis
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-06-01
coleção:	Chemical Physics Impact
Assuntos:	Thiadiazol derivative DFT Molecular docking Admet Lymphatic filariasis
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2667022424000033
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