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Early C-reactive protein reduction predicts survival in real-world extensive-stage small cell lung cancer treated with first-line adebrelimab-based immunotherapy

BackgroundExtensive-stage small cell lung cancer (ES-SCLC) remains an aggressive malignancy with limited biomarkers for predicting outcomes in real-world settings. While baseline systemic inflammation correlates with prognosis, the role of longitudinal inflammation dynamics during PD-L1 inhibitor-ba...

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Principais autores: Jian Wang, Xueli Zhang, Qijia Gao, Jianxin Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-11-01
coleção:Frontiers in Oncology
Assuntos:
extensive-stage small cell lung cancer
C-reactive protein
real-world evidence
adebrelimab
prognostic biomarker
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2025.1709336/full
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