Novel 5-Nitrofuran-Tagged Imidazo-Fused Azines and Azoles Amenable by the Groebke–Blackburn–Bienaymé Multicomponent Reaction: Activity Profile against ESKAPE Pathogens and Mycobacteria

A chemically diverse set of 13 5-nitrofuran-tagged heterocyclic compounds has been prepared via the Groebke–Blackburn–Bienaymé multicomponent reaction. The testing of these compounds against the so-called ESKAPE panel of pathogens identified an apparent lead compound—<i>N</i>-cyclohexyl-2-(5-nitrofu...

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Principais autores:	Alexander Sapegin, Elizaveta Rogacheva, Lyudmila Kraeva, Maxim Gureev, Marine Dogonadze, Tatiana Vinogradova, Petr Yablonsky, Saeed Balalaie, Sergey V. Baykov, Mikhail Krasavin
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2022-09-01
Serija:	Biomedicines
Teme:	Groebke–Blackburn–Bienaymé multicomponent reaction imidazo-fused azines and azoles 5-nitrofurancarboxaldehyde ESKAPE pathogens antibacterial testing antimycobacterial activity
Online dostop:	https://www.mdpi.com/2227-9059/10/9/2203
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