A framework for the design, conduct and interpretation of randomised controlled trials in the presence of treatment changes
Abstract Background When a randomised trial is subject to deviations from randomised treatment, analysis according to intention-to-treat does not estimate two important quantities: relative treatment efficacy and effectiveness in a setting different from that in the trial. Even in trials of a predom...
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| Huvudupphov: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
BMC
2017-10-01
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| Serie: | Trials |
| Ämnen: | |
| Länkar: | http://link.springer.com/article/10.1186/s13063-017-2240-9 |
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