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CDK16 promotes the progression and metastasis of triple-negative breast cancer by phosphorylating PRC1

Abstract Background Cyclin-dependent kinase 16 (CDK16) is an atypical PCTAIRE kinase, and its activity is dependent on the Cyclin Y (CCNY) family. Ccnys have been reported to regulate mammary stem cell activity and mammary gland development, and CCNY has been recognized as an oncoprotein in various...

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Detalhes bibliográficos
Principais autores: Xiao Li, Jinpeng Li, Liming Xu, Wei Wei, Anyi Cheng, Lingxian Zhang, Mengna Zhang, Gaosong Wu, Cheguo Cai
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-04-01
coleção:Journal of Experimental & Clinical Cancer Research
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Acesso em linha:https://doi.org/10.1186/s13046-022-02362-w
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