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Detection of Mycobacterium leprae DNA by polymerase chain reaction in the blood and nasal secretion of Brazilian household contacts

DNA samples from blood and nasal swabs of 125 healthy household contacts was submitted to amplification by polymerase chain reaction (PCR) using a Mycobacterium leprae-specific sequence as a target for the detection of subclinical infection with M. leprae.All samples were submitted to hybridization...

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Principais autores: Elza Carmen de Almeida, Alejandra Nóbrega Martinez, Viviane Câmara Maniero, Ana Maria Sales, Nádia C Duppre, Euzenir Nunes Sarno, Adalberto Rezende Santos, Milton Ozório Moraes
Format: Artigo
Sprog:Inglês
Udgivet: Fundação Oswaldo Cruz (FIOCRUZ) 2004-08-01
Serier:Memorias do Instituto Oswaldo Cruz
Fag:
Mycobacterium leprae
polymerase chain reaction
healthy contacts
early diagnosis
Online adgang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000500009
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