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Spatial Distribution of Immune Cells in Head and Neck Squamous Cell Carcinomas

BackgroundHead and neck squamous cell carcinomas (HNSCCs) have a very moderate response rate to immune checkpoint inhibitor (ICI) treatment compared to other cancer types. Lacking predictive markers for treatment response, we analyzed the immune status of HNSCC and assessed the spatial distribution...

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Autori principali: Christian Idel, Julika Ribbat-Idel, Luise Klapper, Rosemarie Krupar, Karl-Ludwig Bruchhage, Eva Dreyer, Dirk Rades, Christina Polasky, Anne Offermann, Jutta Kirfel, Sven Perner, Barbara Wollenberg
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021-10-01
Serie:Frontiers in Oncology
Soggetti:
HNSCC
immune landscape
spatial distribution
TGF-β
PD-L1
PD-1
Accesso online:https://www.frontiersin.org/articles/10.3389/fonc.2021.712788/full
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