WWOX Phosphorylation, Signaling, and Role in Neurodegeneration
Homozygous null mutation of tumor suppressor WWOX/Wwox gene leads to severe neural diseases, metabolic disorders and early death in the newborns of humans, mice and rats. WWOX is frequently downregulated in the hippocampi of patients with Alzheimer’s disease (AD). In vitro analysis revealed that kno...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2018-08-01
|
| Schriftenreihe: | Frontiers in Neuroscience |
| Schlagworte: | |
| Online-Zugang: | https://www.frontiersin.org/article/10.3389/fnins.2018.00563/full |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|