Large cell neuroblastoma – Phenotypical variant of MYC-driven neuroblastoma: Report of 2 cases with different molecular characteristics

Two rare cases of large cell neuroblastoma (LCN) are reported. Case 1 (8-year-old male) showed the appearance of Neuroblastoma, poorly differentiated subtype with a high MKI (Mitosis-Karyorrhexis Index) and Case 2 (7-year-old male) was Neuroblastoma, undifferentiated subtype with a low MKI. Both cas...

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Detalhes bibliográficos

Principais autores:	Tamás Tornóczky, Bálint Kaszás, Gábor Ottóffy, Diána Hosnyánszki, Réka Simon, Florette K. Hazard, Hiroyuki Shimada
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2021-06-01
coleção:	Human Pathology: Case Reports
Assuntos:	Neuroblastoma Large cell phenotype MYC-driven neuroblastoma n-MYC protein c-MYC protein Nucleolar hypertrophy
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2214330021000225
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