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Development of a highly effective combination monoclonal antibody therapy against Herpes simplex virus

Abstract Background Infections with Herpes simplex virus (HSV)-1 or -2 usually present as mild chronic recurrent disease, however in rare cases can result in life-threatening conditions with a large spectrum of pathology. Monoclonal antibody therapy has great potential especially to treat infections...

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Principais autores: Narges Seyfizadeh, David Kalbermatter, Thomas Imhof, Moritz Ries, Christian Müller, Leonie Jenner, Elisabeth Blumenschein, Alexandra Yendrzheyevskiy, Frank Grün, Kevin Moog, Daniel Eckert, Ronja Engel, Philipp Diebolder, Mohamed Chami, Jürgen Krauss, Torsten Schaller, Michaela Arndt
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-05-01
Colecção:Journal of Biomedical Science
Assuntos:
Herpes simplex virus (HSV)
Glycoprotein B (gB)
Therapeutic monoclonal antibody
Combination therapy
Acesso em linha:https://doi.org/10.1186/s12929-024-01045-2
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