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The cortical actin determines different susceptibility of naïve and memory CD4+ T cells to HIV-1 cell-to-cell transmission and infection.

Memory CD4+ T cells are preferentially infected by HIV-1 compared to naïve cells. HIV-1 fusion and entry is a dynamic process in which the cytoskeleton plays an important role by allowing virion internalization and uncoating. Here, we evaluate the role of the cortical actin in cell-to-cell transfer...

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Hlavní autoři: Marc Permanyer, Eduardo Pauls, Roger Badia, José A Esté, Ester Ballana
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2013-01-01
Edice:PLoS ONE
On-line přístup:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24244453/?tool=EBI
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