Development and Evaluation of Compact Semi-Synthetic Promoters for Enhanced Antigen Expression in Adenoviral-Vectored Vaccines

Background/Objectives: The large size of commonly used regulatory elements such as the cytomegalovirus (CMV) immediate-early promoter imposes a significant burden on the already restricted payload capacity of first-generation adenoviral vectors, potentially hindering the development of multi-antigen...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Matěj Hlaváč, Susan J. Morris, Barbara Dema, Marta Ulaszewska, Zakia Al-Hareth, Bruno Douradinha, Sarah C. Gilbert
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2026-03-01
Цуврал:	Vaccines
Нөхцлүүд:	adenoviral-vector vaccines ChAdOx1 synthetic promoters antigen expression
Онлайн хандалт:	https://www.mdpi.com/2076-393X/14/3/260
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!