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Type I Diabetes-Associated Tolerogenic Properties of Interleukin-2

Type 1 Diabetes (T1D) results from insulin-producing beta cells destruction by diabetogenic T lymphocytes in humans and nonobese diabetic (NOD) mice. The breakdown of tolerance has been associated with a defect in the number and the function of naturally occurring regulatory T cells (nTreg) that are...

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Bibliografische gegevens
Hoofdauteurs: Aziz Alami Chentoufi, Simon Gaudreau, Alex Nguyen, Mahmoud Sabha, Abdelaziz Amrani, Geyhad ElGhazali
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Wiley 2011-01-01
Reeks:Clinical and Developmental Immunology
Online toegang:http://dx.doi.org/10.1155/2011/289343
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