Predictive biomarkers for low-dose IL-2 therapy efficacy in systemic lupus erythematosus: a clinical analysis

Abstract Background Low-dose IL-2 (Ld-IL2) has shown favorable therapeutic effects in systemic lupus erythematosus (SLE) therapy. However, previous clinical trials reported an SLE Responder Index-4 (SRI-4) response rate of 65.52%-68%, with approximately half failing to achieve the primary endpoint b...

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Huvudupphov:	Ruiling Feng, Xian Xiao, Bo Huang, Kai Zhang, Xia Zhang, Zhanguo Li, Yuan Jia, Jing He
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	BMC 2024-10-01
Serie:	Arthritis Research & Therapy
Ämnen:	Low-dose IL-2 Systemic lupus erythematosus SLE Responder Index-4 (SRI-4) Efficacy responses Predictive factors
Länkar:	https://doi.org/10.1186/s13075-024-03388-5
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