Genomic and Clinical Correlates of Adrenocortical Carcinoma in an Adult Patient with Li-Fraumeni Syndrome: A Case Report

Li-Fraumeni Syndrome (LFS) is defined by germline mutations of the p53 tumour suppressor gene. Adrenocortical carcinoma (ACC) is a rare aggressive malignancy that is commonly associated with LFS. Most LFS-linked ACC cases occur in children, and limited research has been dedicated to the clinical out...

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Hlavní autoři:	Suraya Bondy, Camilla Tajzler, Sebastien J. Hotte, Anil Kapoor, Kevin Zbuk, Aly-Khan A. Lalani
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2020-12-01
Edice:	Current Oncology
Témata:	Li-Fraumeni Syndrome adrenocortical carcinoma next-generation sequencing
On-line přístup:	https://www.mdpi.com/1718-7729/28/1/25
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