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Reinfection and ceftriaxone tolerance in a clinical case of recurrent gonorrhoea: a case report supported by in vitro and in vivo models

BackgroundAntibiotic tolerance slows bacterial killing during drug exposure without changing minimum inhibitory concentration (MIC) and is often missed by MIC-based testing in Neisseria gonorrhoeae.ObjectivesTo quantify ceftriaxone tolerance using complementary laboratory assays and to integrate the...

Deskribapen osoa

Gorde:
Egile Nagusiak: Izumo Kanesaka, Saïd Abdellati, Thibaut Vanbaelen, Irith De Baetselier, Tessa de Block, Basil Britto Xavier, Chris Kenyon, Sheeba Santhini Manoharan-Basil
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2026-04-01
Saila:Frontiers in Cellular and Infection Microbiology
Gaiak:
ceftriaxone
MDK99
Neisseria gonorrhoeae
reinfection
tolerance
treatment failure
Sarrera elektronikoa:https://www.frontiersin.org/articles/10.3389/fcimb.2026.1720396/full
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