Polygenic scores in Familial breast cancer cases with and without pathogenic variants and the risk of contralateral breast cancer

Abstract Background Polygenic risk scores (PRS) are not yet standard in clinical risk assessments for familial breast cancer in Sweden. This study evaluated the distribution and impact of an established PRS (PRS313) in women undergoing clinical sequencing for hereditary breast cancer. Findings We in...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Anders Kvist, Anders Kämpe, Therese Törngren, Bianca Tesi, Panagiotis Baliakas, Åke Borg, Daniel Eriksson
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2025-09-01
Цуврал:	Breast Cancer Research
Онлайн хандалт:	https://doi.org/10.1186/s13058-025-02107-5
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!