EP4-induced mitochondrial localization and cell migration mediated by CALML6 in human oral squamous cell carcinoma

Abstract Lymph node metastasis, primarily caused by the migration of oral squamous cell carcinoma (OSCC) cells, stands as a crucial prognostic marker. We have previously demonstrated that EP4, a subtype of the prostaglandin E2 (PGE2) receptor, orchestrates OSCC cell migration via Ca2+ signaling. The...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Soichiro Ishikawa, Masanari Umemura, Rina Nakakaji, Akane Nagasako, Kagemichi Nagao, Yuto Mizuno, Kei Sugiura, Mitomu Kioi, Kenji Mitsudo, Yoshihiro Ishikawa
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2024-05-01
Schriftenreihe:	Communications Biology
Online-Zugang:	https://doi.org/10.1038/s42003-024-06231-4
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