Mendelian randomization study of lipid metabolites reveals causal associations with age-related macular degeneration

Background: Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in the elderly, affecting approximately 8.7 % of individuals over 55 years old. Increasing evidence suggests that lipid metabolism plays a significant role in AMD pathogenesis, yet the causal relationsh...

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Hauptverfasser:	Miao Shui, Guoke Yang, Jiang Jiang, Sibo Wang, Rongfeng Liao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2025-09-01
Schriftenreihe:	Experimental Gerontology
Schlagworte:	Mendelian randomization Age-related macular degeneration Lipid metabolites Laurate Dehydroisoandrosterone sulfate Palmitoyl sphingomyelin
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S0531556525001469
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