Application of next-generation sequencing to characterize novel mutations in clarithromycin-susceptible Helicobacter pylori strains with A2143G of 23S rRNA gene

Abstract Background Clarithromycin (CLR) resistance has become a predominant factor for treatment failure of Helicobacter pylori eradication. Although the molecular mechanism of CLR resistance has been clearly understood in H. pylori, it is lack of evidence of other genes involved in drug resistance...

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Автори:	Jiaoe Chen, Liping Ye, Liangmin Jin, Xuehua Xu, Peisong Xu, Xianjun Wang, Hongzhang Li
Формат:	Artigo
Мова:	Inglês
Опубліковано:	BMC 2018-03-01
Серія:	Annals of Clinical Microbiology and Antimicrobials
Предмети:	Helicobacter pylori Clarithromycin Susceptible strains 23S rRNA SNVs RND family
Онлайн доступ:	http://link.springer.com/article/10.1186/s12941-018-0259-8
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