Metabolomic Markers of Left Ventricular Structure, Diastolic Function, and Risk of Coronary Heart Disease: A Longitudinal Study in American Indian Individuals

Background Subclinical alterations in left ventricular (LV) structure, diastolic function, and metabolic disturbances are associated with coronary heart disease (CHD) risk, but their relationships remained unclear. Large‐scale longitudinal metabolomic profiling of LV measures is lacking. Methods Usi...

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Detalhes bibliográficos

Principais autores:	Mingjing Chen, Yixi Sun, Guanhong Miao, Xiaoxiao Wen, Alexander C. Razavi, Camilo Fernandez, Mary J. Roman, Richard B. Devereux, Richard R. Fabsitz, Ying Zhang, Jason G. Umans, Shelley A. Cole, Lydia A. Bazzano, Oliver Fiehn, Tanika N. Kelly, Jinying Zhao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2026-02-01
coleção:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Assuntos:	American Indians coronary heart disease left ventricular diastolic function left ventricular structure metabolomics Strong Heart Family Study
Acesso em linha:	https://www.ahajournals.org/doi/10.1161/JAHA.125.044310
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