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Nonradioactive Characterization of Low-Level Heteroplasmic Mitochondrial DNA Mutations by SSCP-PCR Enrichment

Mitochondrial DNA (mtDNA) mutations have been implicated in an increasing number of human diseases. Many of these mutations are heteroplasmic and are only present at low levels in readily accessible human tissue such as blood. The technique of single-stranded conformational polymorphism (SSCP) allow...

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Bibliografski detalji
Glavni autori: Emma J. Sherratt, Andrew W. Thomas, James W. Gagg, John C. Alcolado
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis Group 1996-03-01
Serija:BioTechniques
Online pristup:https://www.future-science.com/doi/10.2144/19962003430
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