Deep phenotyping of surface stimulatory and inhibitory co-receptors on cancer-resident T and NK cells reveals cell subsets within the tumor-reactive CTL population that are uniquely defined by NKG2A expression

The field of Immuno-Oncology (IO) is evolving to utilise novel antibody backbones that can co-target multiple cell-surface stimulatory and inhibitory co-receptors (SICR). This approach necessitates a better understanding of SICR co-expression at the single-cell level on IO-relevant tumor-infiltratin...

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Auteurs principaux:	James Hair, Matthew J Robinson, Robert W Wilkinson, Simon J Dovedi
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2022-03-01
Collection:	SLAS Discovery
Sujets:	Immuno-oncology Cytometry Phenotyping Lymphocytes
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2472555221000204
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