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MiRNA-20b/SUFU/Wnt axis accelerates gastric cancer cell proliferation, migration and EMT

Previous research has found that miRNA-20b is highly expressed in gastric cancer (GC), however, its function and underlying mechanism are not clear. Wnt signaling pathway, implicated in tumorigeneisis, is activated in more than 30% of GC. We would like to characterize the biological behavior of miRN...

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Auteurs principaux: Yin Peng, Ying Qin, Xiaojing Zhang, Shiqi Deng, Yuan Yuan, Xianling Feng, Wangchun Chen, Fan Hu, Yuli Gao, Jieqiong He, Yulan Cheng, Yanjie Wei, Xinmin Fan, Hassan Ashktorab, Duane Smoot, Song Li, Stephen J. Meltzer, Shutong Zhuang, Na Tang, Zhe Jin
Format: Artigo
Langue:Inglês
Publié: Elsevier 2021-04-01
Collection:Heliyon
Sujets:
miRNA-20b
SUFU
EMT
Wnt/β-catenin
Accès en ligne:http://www.sciencedirect.com/science/article/pii/S2405844021007982
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