Rickettsia disrupts and reduces endothelial tight junction protein zonula occludens-1 in association with inflammasome activation

ABSTRACT Rickettsia spp. cause life-threatening diseases in humans. The fundamental pathophysiological changes in fatal rickettsial diseases are disrupted endothelial barrier and increased microvascular permeability. However, it remains largely unclear how rickettsiae induce microvascular endothelia...

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Үндсэн зохиолчид:	Loka Reddy Velatooru, Esteban Arroyave, Meagan D. Rippee-Brooks, Megan Burch, Ethan Yang, Bing Zhu, David H. Walker, Yang Zhang, Rong Fang
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Microbiology 2025-01-01
Цуврал:	Infection and Immunity
Нөхцлүүд:	inflammasome ZO-1 Rickettsia endothelial cells tight junction
Онлайн хандалт:	https://journals.asm.org/doi/10.1128/iai.00468-24
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!