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Convergent transcriptomic signature in iPSC-dopaminergic neurons of hereditary Parkinson’s disease

Study reveals that two distinct genetic causes of Parkinson’s disease push brain cells onto the same harmful path, increasing their vulnerability long before symptoms appear. The clinical and genetic diversity of Parkinson’s disease (PD) makes it challenging to identify common mechanisms across diff...

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Hlavní autoři: Irina V Kopylova, Artem B Ivanov, Lev R Eidelman, Ekaterina N Zaitseva, Ekaterina D Kulikova, Dmitriy A Grehnyov, Alexandra N Bogomazova, Vladimir A Vigont, Elena V Kaznacheyeva, Maria A Lagarkova, Olga S Lebedeva, Evgenii I Olekhnovich
Médium: Artigo
Jazyk:Inglês
Vydáno: Life Science Alliance LLC 2026-07-01
Edice:Life Science Alliance
On-line přístup:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202503551
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