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N 6-methyladenosine modification is not a general trait of viral RNA genomes

Abstract Despite the nuclear localization of the m6A machinery, the genomes of multiple exclusively-cytoplasmic RNA viruses, such as chikungunya (CHIKV) and dengue (DENV), are reported to be extensively m6A-modified. However, these findings are mostly based on m6A-Seq, an antibody-dependent techniqu...

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Principais autores: Belinda Baquero-Pérez, Ivaylo D. Yonchev, Anna Delgado-Tejedor, Rebeca Medina, Mireia Puig-Torrents, Ian Sudbery, Oguzhan Begik, Stuart A. Wilson, Eva Maria Novoa, Juana Díez
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2024-03-01
Series:Nature Communications
Acceso en liña:https://doi.org/10.1038/s41467-024-46278-9
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