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The Role of Pro-Opiomelanocortin Derivatives in the Development of Type 2 Diabetes-Associated Myocardial Infarction: Possible Links with Prediabetes

Myocardial infarction is a major contributor to CVD-related mortality. T2DM is a risk factor for MI. Stress activates the HPA axis, SNS, and endogenous OPS. These POMC derivatives increase the blood glucose and cardiovascular response by inhibiting the PI3K/AkT insulin signaling pathway and increasi...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Nompumelelo Anna-Cletta Gumede, Andile Khathi
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2024-01-01
Schriftenreihe:Biomedicines
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Online-Zugang:https://www.mdpi.com/2227-9059/12/2/314
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