KLF11 alleviates rheumatoid arthritis by regulating M1 macrophage polarization via downregulation of YAP1 expression

Abstract Rheumatoid arthritis (RA) is a chronic autoimmune disease, primarily impacting joints and bones. The Gene Expression Omnibus (GEO) datasets (GSE55235 and GSE10500) revealed that KLF11 expression was lower in the patients with RA, which was confirmed by the collected RA samples. However, KLF...

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Hlavní autoři:	Xiaodan Liu, Fang Fang, Hongmei Duan, Chunling Wu, Haina Liu, Shuang Ding
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-08-01
Edice:	Arthritis Research & Therapy
Témata:	Rheumatoid arthritis Krüppel-like factor 11 Macrophage polarization Yes-associated protein 1 ERK signaling pathway
On-line přístup:	https://doi.org/10.1186/s13075-025-03634-4
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