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Caffeine May Abrogate LPS-Induced Oxidative Stress and Neuroinflammation by Regulating Nrf2/TLR4 in Adult Mouse Brains

Herein, we assayed the antioxidant and anti-inflammatory potential of caffeine in a lipopolysaccharide (LPS)-injected mouse model of neurodegeneration and synaptic impairment. For this purpose, LPS was injected for two weeks on an alternate-day basis (250 µg/kg/i.p. for a total of seven doses),...

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Principais autores: Haroon Badshah, Muhammad Ikram, Waqar Ali, Sareer Ahmad, Jong Ryeal Hahm, Myeong Ok Kim
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-11-01
Colecção:Biomolecules
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Acesso em linha:https://www.mdpi.com/2218-273X/9/11/719
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