A novel radiosensitizer α-sulfoquinovosyl-acylpropanediol (SQAP) inhibits DNA repair pathways and sensitize cells to cancer chemotherapeutic agents

Abstract Sulfoglycolipid, α-sulfoquinovosyl-acylpropanediol (SQAP) is a novel veterinary radiosensitizer, which is known to cause angiogenesis alteration and sensitizes hypoxic tumors in the in vivo animal model. We examined the SQAP radio/chemo-sensitization mechanisms from DNA repair with canine c...

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Principais autores:	Junko Maeda, Shigeaki Sunada, Takaomi Fukuhara, Takamitsu A. Kato
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-11-01
Colecção:	Scientific Reports
Assuntos:	Α-sulfoquinovosyl-acylpropanediol DNA repair Chemotherapeutic agents Cancer Chemosensitizer
Acesso em linha:	https://doi.org/10.1038/s41598-025-25524-0
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