A bioinformatic analysis of T-cell epitope diversity in SARS-CoV-2 variants: association with COVID-19 clinical severity in the United States population

Long-term immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) requires the identification of T-cell epitopes affecting host immunogenicity. In this computational study, we explored the CD8+ epitope diversity estimated in 27 of the most common HLA-A and HLA-B alleles, repres...

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Bibliografske podrobnosti

Principais autores:	Grace J. Kim, Jacob H. Elnaggar, Mallory Varnado, Amy K. Feehan, Darlene Tauzier, Rebecca Rose, Susanna L. Lamers, Maya Sevalia, Najah Nicholas, Elizabeth Gravois, Daniel Fort, Judy S. Crabtree, Lucio Miele
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2024-05-01
Serija:	Frontiers in Immunology
Teme:	SARS-CoV-2 T cell epitope COVID-19 bioinformatics CD8 T cell epitope HLA
Online dostop:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1357731/full
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