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Does Chemotherapy-Induced Gastrointestinal Mucositis Affect the Bioavailability and Efficacy of Anti-Infective Drugs?

Antimicrobial prophylaxis is increasingly being used in patients with hematological malignancies receiving high-dose chemotherapy and hematopoietic stem cell transplantation (HSCT). However, few studies have focused on the potential impact of gastrointestinal mucositis (GI-M), a frequently observed...

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Principais autores: Ana Rita da Silva Ferreira, Anne-Grete Märtson, Alyse de Boer, Hannah R. Wardill, Jan-Willem Alffenaar, Hermie J. M. Harmsen, Wim J. E. Tissing
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-10-01
Serier:Biomedicines
Fag:
cancer
chemotherapy
gastrointestinal mucositis
antibiotics
gut microbiota
drug pharmacokinetics
Online adgang:https://www.mdpi.com/2227-9059/9/10/1389
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