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The pro-inflammatory effect of Staphylokinase contributes to community-associated Staphylococcus aureus pneumonia

Staphylokinase (Sak) is highly prevalent in human-adapted S. aureus strains, with increased expression in community-associated (CA-SA) strains, promoting lung infection and activation of the NLRP3 inflammasome.

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Dades bibliogràfiques
Autors principals: Yanan Wang, Na Zhao, Ying Jian, Yao Liu, Lin Zhao, Lei He, Qian Liu, Min Li
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2022-06-01
Col·lecció:Communications Biology
Accés en línia:https://doi.org/10.1038/s42003-022-03571-x
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