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Doxorubicin-Loaded Core–Shell UiO-66@SiO<sub>2</sub> Metal–Organic Frameworks for Targeted Cellular Uptake and Cancer Treatment

Beneficial features of biocompatible high-capacity UiO-66 nanoparticles, mesoporous SiO<sub>2</sub>, and folate-conjugated pluronic F127 were combined to prepare the core–shell UiO-66@SiO<sub>2</sub>/F127-FA drug delivery carrier for targeted cellular uptake in cancer treatment. UiO-66 and UiO-66-NH...

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Principais autores: Daria B. Trushina, Anastasiia Yu. Sapach, Olga A. Burachevskaia, Pavel V. Medvedev, Dmitry N. Khmelenin, Tatiana N. Borodina, Mikhail A. Soldatov, Vera V. Butova
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-06-01
Serier:Pharmaceutics
Fag:
nano-MOF
nanoparticles
UiO-66
MOF
silanization
silica shell
Online adgang:https://www.mdpi.com/1999-4923/14/7/1325
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